Pittsburgh Steelers quarterback Kenny Pickett will reportedly miss two-to-four weeks with a right ankle injury he sustained in Sunday's game against the Arizona Cardinals.

According to the Pittsburgh Post-Gazette, Pickett will undergo surgery Monday and will be evaluated further following the procedure, leaving open the possibility he could be sidelined for a period longer than his initial timetable. 

Pickett was injured on a scramble attempt near the goal line during the second quarter of Pittsburgh's 24-10 loss to the Cardinals. The second-year pro was ruled out at half-time and had his right foot in a walking boot while on the sidelines during the second half.

Veteran Mitch Trubisky replaced Pickett and will start the Steelers' game against the New England Patriots on Thursday.

Sources: Kenny Pickett to have ankle surgery Monday, expected to miss 2-4 weeks https://t.co/au5aoZJ9vl via @PittsburghPG

— Gerry Dulac (@gerrydulac) December 4, 2023

Trubisky began last season as Pittsburgh's No. 1 quarterback before being displaced by the then-rookie Pickett after four games. The former Chicago Bears' first-round pick went 2-3 in five overall starts in 2022 while compiling 1,252 passing yards with four touchdowns and five interceptions over seven total games.

Pickett completed seven of 10 passes for 70 yards before exiting to extend his franchise-record streak of pass attempts without an interception to 218, the longest streak of any quarterback this season as well. The 2022 first-round pick has not thrown an interception in eight consecutive starts to help put the Steelers in position for a playoff spot in the AFC.

At 7-5, Pittsburgh is one of four teams currently tied in the race for the conference's three wild card spots. The Steelers trail the first-place Baltimore Ravens by two games in the AFC North with five left to play.

For the season, Pickett has thrown for 2,070 yards with six touchdowns and four interceptions while completing 62 per cent of his pass attempts in 12 starts.