Aryna Sabalenka will face either Jessica Pegula or Emma Navarro in the US Open semi-finals after she beat Linda Noskova in a thriller.
Alexander Zverev's hopes of winning a first US Open title are still alive after a comfortable last-16 victory over Luciano Darderi.
Coco Gauff prevailed in an all-American clash with Iva Jovic at the US Open, with Mirra Andreeva up next in the quarter-finals.
Elena Rybakina reached the US Open quarter-finals for the first time after beating Naomi Osaka, with the world number one spot now in sight.
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