The New York Giants will be without starting quarterback Daniel Jones Sunday night when they visit the Buffalo Bills.

Jones, who left the Giants' 31-16 loss to the Miami Dolphins last weekend with a neck injury, was ruled out Friday by New York coach Brian Daboll.

Veteran Tyrod Taylor will make his first start since 2021 in Jones' place.

Jones was hurt when he was sacked by Miami's Andrew Van Ginkel, the sixth time he was sacked during the game. Jones has been sacked 28 times this season, the second most in the league behind only Sam Howell (29).

Jones missed six games in 2021 with a neck injury, but the fifth-year pro told reporters this week that his current ailment is unrelated.

Jones, who signed a four-year, $160million contract extension in March, has struggled this season with a career-low 71.7 passer rating. After throwing just five interceptions last season, Jones has thrown six already this year.

The Giants (1-4) have lost three straight games and are in last place in the NFC East. New York will also be without left tackle Andrew Thomas, rookie center John Michael Schmitz, outside linebacker Azeez Ojulari and backup tackle Matt Peart on Sunday.

Star running back Saquon Barkley, who has missed the last three games with an ankle injury, returned to practice this week and is expected to have a chance of playing against Buffalo.

From The Insiders on #NFLPlus: #Giants QB Daniel Jones is out for Sunday vs. the #Bills, setting up a Tyrod Taylor revenge game. pic.twitter.com/Le5RaPkjyI

— Ian Rapoport (@RapSheet) October 13, 2023